RESEARCH ACTIVITIES

Ph.D COMPLETED/PERSUING

A no. of Faculty members have completed their Ph.D work availing the facilities of the Institute. Moreover a no. of Faculty members are still pursuing their Ph.D work at the Institute. The list of Faculty members who have completed and pursuing their Ph.D dissertation are as follows

NAME OF FACULTY Phd Topic PhD AWARDED FROM YEAR OF AWARD
Dr. Monika Sachdeva Preparation and evaluation of polyherbal hepatoprotective formulations UTU, Dehradun APRIL .2014
Dr. Vishwanath Agrahari Development and validation of stability indicating analytical methods for some drugs MDU, Rohtak MAY 2015
Dr. Munendra Mohan Varshney Synthesis, characterization and biological evaluation of some newer imines UTU, Dehradun APRIL 2015
Dr. Dilip Gupta Development and evaluation of nanoparticles for delivery of antimalarial drugs UTU, Dehradun APRIL 2015
Dr. Vijay Agarwal Dissolution enhancement of poorly water soluble drugs using nanosuspension technology NIMS, Jaipur JULY 2017
Dr. Sunil Khatak Central composite designed solid lipid nanoparticles MDU, Rohtak MARCH 2019

M.PHARM / B.PHARM PROJECTS

The Institute also provides facilities for the completion of PG and UG projects as per the prescribed curricula. A list of such projects, completed/ pursued during the last two academic years is as follows –

  1. Design Characterization and Optimization of Controlled Drug Delivery System of poorly Water Soluble Drug.
  2. Formulation and evaluation of transdermal patches of plumbago zeylamica root extract on anti fungal activities.
  3. Formulation Development and Evaluation of Gemifloxacin Dispersible Tablet.
  4. Design and formulation of a lotion containing calcipotriol in the treatment of psoriasis
  5. Formulation Development optimization and characterization of fabricated nanocrystal using poorly soluble drug.
  6. Formulation and characterization of gastro retentive floating microbaloon of poorly water soluble drug Diacerin To optimize and evaluate the oral dispersible tablet of Antidiabitic Drug teneligliptin
  7. Formulation Development and Evaluation of Nanostructured Lipid Carriers Encapsulated Antifungal Drug Emulgel.
  8. Formulation Development and Characterization of Nadifloxacin Loaded Solid Lipid nanoparticles Hydrogel.
  9. Development and evaluation of oral self nanoemulsifying drug delivery system for poorly soluble drug
  10. Development and evaluation of encapsulated solid lipid nanoparticles of clopidogrel bisulfate
  11. Formulation and evaluation of liquid self micro emulsion drug delivery system of tolnaftate
  12. Formulation and evaluation of nanoemulsion system for topical delivery of mupirocin
  13. Formulation and developement of topical hydrogel of baricitinib by using natural and synthetic polymers
  14. Topic, development and characterization of esomeprazole nanosuspension as an oral drug delivery system
  15. Formulation and evaluation of eplerenone by solid dispersion technique
  16. Combined 3D-QSAR and molecular docking study on benzo[h] naphthyriding-21(H)-one analogues as mTOR inhibitors
  17. QSAR studies of 1,4-dihydropyriding derivative as anticancer agent
  18. 2DQSAR studies of some novel triazolo-B- lactam derivatives for their anti-inflammatory activity
  19. 2DQSAR study of 1,2,4 triazole, beta-chlorpropamide antitubercular activity
  20. A survey on knowledge and perception of materiovigilance among health care professional Management of Sinusitis
  21. A survey on self medication among pharmacy students.
  22. ADR reporting of antidiabetic drugs.
  23. Comparative study of BMI of rural and urban population
  24. Novartis ag & anr vs. cipla ltd. (patent infringement)
  25. The patent of turmeric case
  26. Natco pharma ltd. Vs Bayer compulsory licensing regime in India
  27. The battle over sitagliptin b/w Merck and glenmark
  28. The patent infringement case -nexium
  29. Cipla vs. Roche over erlotinib
  30. Merck sharp & dohme corporation & anr vs glenmark phaRrmaceuticals pvt. Ltd.
  31. F.hoffmann la-roche vs. cipla ltd
  32. Preparation of SOP for collection and preparation of reference samples (raw materials and finished goods)
  33. GMP requirements for external preparation
  34. GMP requirements for liquid oral preparation
  35. Prepare a document for implementation of Good Laboratory Practice (GLP).
  36. Comparative study of amoxicillin capsule of 4 brands available in market
  37. Batch processing records on large volume parenterals
  38. Preparation and evaluation of ofloxacin tablet and compare with 3 market brands
  39. GMP requirement of biological products
  40. Batch processing record of tablet

PUBLICATIONS

The Faculty and students of the Institute regularly communicate the findings of their researches in various Journals of national and International repute. The list of such publications during the last six academic years is as follows -

  • Munendra Mohan Varshney, Asif Husain, Versha Parcha, “Synthesis and characterization of 5-(substituted phenyl)-2-furfuraldehydes from substituted anilines” World Journal of Pharmacy and Pharmaceutical Sciences, 2(4), 1802-1806, 2013. Impact factor 1.02
  • Munendra Mohan Varshney, Asif Husain, Versha Parcha, “Synthesis, characterization, in-vitro antimicrobial and anthelmintic evaluations of 2-(4-chloro-3-methylphenoxy)-N’-[{5’-(substitutedaryl)-furan-2’-yl}-methylidene]-cetohydrazides” Medicinal Chemistry Research, Springer publication. 2014, 23: 4034-4041, (Impact factor 1.70, Thomson reuters)
  • Munendra Mohan Varshney, Asif Husain, Versha Parcha, “Synthesis, characterization and biological evaluations of 2-(4-hydroxyaryl)–N’-{5’-(substitutedaryl)-furan-2’-yl)-methylidene}-ketohydrazides Schiff bases” Der Pharma Chemica, 2014, 6(1): 241-247 (Impact factor 0.48, Thomson reuters)
  • Munendra Mohan Varshney, Asif Husain, Versha Parcha et al, “Synthesis and biological evaluation of some new hydrazides” Bangladesh Journal of Pharmacology, 2015, 10: 555-561. (Impact factor 1.06, Thomson reuters)
  • Munendra Mohan Varshney, Asif Husain, Versha Parcha et al, “Nalidixic acid Schiff bases: synthesis and biological evaluation” Letters in drug design and discovery, 2018, 15, 103-111. (Impact factor 1.05, Thomson reuters)
  • Munendra Mohan Varshney, Seema, Abhinav Agarwal, ” Preformulation, preparation and evaluation of nanoemulsion containing antibacterial drugs” World Journal of Pharmacy and Pharmaceutical Sciences, 2019, 8(9). 1205-1225.
  • Vijay Agarwal, Surya Goel, Monika Sachdeva. Development and Characterization of Oral Nanosuspension using Esomeprazole Magnesium Trihydrate. Nanoscience and Nanotechnology: Asia. 2020, 10. (Bentham Science Publisher)
  • Vijay Agarwal, Surya Goel, Monika Sachdeva. Nanosuspension Technology: Recent patents on drug delivery and their characterizations. Recent patents on drug delivery and formulations. 2019, 13, 91-104. (Bentham Science Publisher)
  • Vijay Agarwal, Meenakshi Bajpai, Ashish Sharma. Patented and approval scenario of nanopharmaceuticals with relevancy to biomedical application, manufacturing procedure and safety aspects. Recent patents on drug delivery and formulations 2018, 12, 40-52. (Bentham Science Publisher, Scopus Indexed)
  • Vijay Agarwal, Meenakshi Bajpai. Nanosuspension Technology For Poorly Soluble Drugs: Recent Researches, Advances and Patents. Recent patents on nanotechnology 2015, 9 (3), 178-194. (Bentham Science Publisher, impact factor 2.57, ISSN: 2212-4020).
  • Vijay Agarwal, Meenakshi Bajpai. Preparation and Optimization of esomeprazole nanosuspension using evaporative precipitation- ultrasonication. Tropical journal of pharmaceutical research 2014, 13(4), 497-503 (impact factor 0.82, ISSN: 1596-9827).
  • Vijay Agarwal, Meenakshi Bajpai. Investigation of formulation and process parameters for the production of esomeprazole nanosuspension by anti-solvent precipitation ultrasonication technique. Current Nanoscience 2013, 9, 773-779 (Bentham Science publisher, impact factor 1.42, ISSN: 1875-6786).
  • Vijay Agarwal, Devendra S Rathore, Meenakshi bajpai. Investigation of effect of nonionic stabilizers on the physical stability of drug nanosuspension prepared by bottom up approach. International Journal of Pharmaceutical Sciences and Drug Research 2016, 8 (4), 189-198 (impact factor 0.53, ISSN: 0975-248X).
  • Vijay Agarwal, Meenakshi Bajpai. Nanosuspension Technology: A Strategic approach for poorly soluble drugs. Nanoscience and Nanotechnology Asia 2013, 3, 72-85 (Bentham Science publisher, ISSN: 2210-6820).
  • Vijay Agarwal, Meenakshi Bajpai. Stability Issues related to nanosuspenssion : A Review. Pharmaceutical Nanotechnology 2013, 1, 85-92 (Bentham Science Publisher, ISSN: 2211-7393).
  • Vijay Agarwal, Rahul Mishra, Dr. UVS Sara. Controlled porosity osmotic pump tablet : A review. International Journal of Universal Pharmacy and Bio Sciences 2013, 2(1), 258-270 (ISSN: 2319-8141).
  • Vishwanath Agrahari, Meenakshi Bajpai, Sanju Nanda, “Development and validation of a stability indicating HPLC method for analysis of Pefloxacin in bulk drug and tablet dosage form”. Int J Pharm Pharm Sci, 2013, 5(2), 263-268 (ISSN- 0975-1491)
  • Vishwanath Agrahari, Meenakshi Bajpai, Sanju Nanda, “Essential Concepts of Mobile Phase Selection for Reversed Phase HPLC”. Research J. Pharm. and Tech. 2013, 6(5), 459-464
  • Vishwanath Agrahari, Meenakshi Bajpai, Sanju Nanda, “Development of a simple UV- spectrophotometric assay method for Satranidazole and study of its degradation profile”.Int. Res. J. Pharm. 2013, 4(4), 209-213
  • Monika Sachdeva, Meenakshi Bajpai, B.K.Razdan. Hepatoprotective activity of a polyherbal preparation against D-galactosamine induced hepatoxicity in rats. RJPT , Volume : 6, Issue : 9, 20013,1079-1082
  • Monika Sachdeva, Meenakshi Bajpai, B.K.Razdan. Toxicity studies of a developed hepatoprotective formulation. Asian J Pharm Clin Res, Vol 6 Issue 4, 2013, 47-50
  • Mishra S, Sachdeva M, Sara UVS. Vesicular and provesicular Drug carriers: An overview. Inventi Rapid: NDDDS, 2013(2)
  • Mishra S, Vasistha P, Sachdeva M, Sara UVS. Formulation, Optimization and characterization of proniosomal gel for transdermal delivery of Naproxen. World J .Pharmacy & Pharm.Sci. 2(2): 554-569.
  • Kirti Kumari, UVS. Sara, Monika Sachdeva. Formulation and Evaluation of Topical Hydrogel of Mometasone Furoate using Different Polymers. IJPCS; Vol. 2 (1) Jan-Mar 2013.
  • Abhinav Agrawal, Tarun Virmani, Jyoti Gupta . Effect of formulation variables on the release behavior of microspheres. Int. Res. J. Pharm. 2018;9(8)
  • Abhinav Agrawal, Amrish Kumar et al. A review on pharmacological treatment of sleep and circadian rhythm disorders. Sleep Medicine and Disorders: International Journal. Volume 3 Issue 1 – 2019
  • Neha Rana ,Vijender singh, , Mohd.Ali: GC-MS Analysis and Antimicrobial activities of volatile oil of Nardostachys jatamansi D.C. rhizomes obtained from Haridwar region,Uttarakhand. Pharmacognosy Journal.2018;10(2): 230-234
  • Mishra Supriya, Sharma Shrestha, N Javed “Bioinspired Nanocomposites: application in disease diagnosis and treatment”. Pharmaceutical Nanotechnology, Bentham science publishers 2019, 7,206-219.
  • Sehrawat Renu, Khatak Mamta, Maithani Mukesh and Khatak Sunil, 2013. Simultaneous determination of chlorpheniramine maleate, paracetamol and phenylephrine hydrochloride in tablet dosage form by high performance liquid chromatography. Int. J. Drug Dev. Res. 5(1): 258-263. (ISSN 0975-9344, Impact Factor: 0.21)
  • Sehrawat Renu, Khatak Mamta, Maithani Mukesh and Khatak Sunil, 2013. Development and validation of chlorpheniramine maleate and phenylephrine hydrochloride by RPHPLC. Int. J. Pharmaceutica Sciencia. 4(8): 209-214.
  • Neha Yadav, Sunil Khatak and Udai Vir Singh Sara, 2013. Solid Lipid Nanoparticles – A Review. Int J App Pharmaceutics, 5(2): 8-18. (ISSN: 2231-5896)
  • Navinder, Mamta Khatak, Renu Sehrawat, and Sunil Khatak, 2013. A comparative study: Homoeopathic medicine and a medicinal plant withania somnifera for antidiabetic activity. Journal of Pharmacognosy and Phytochemistry, 2 (3): 109-112. (ISSN (Online): 2278-4136, ISSN (Print) : 2349-8234, GIF : 0.255, ICV : 5.52)
  • Sunil Khatak and Harish Dureja, 2015. Recent Advances in Nanotechnology based Tubercular Chemotherapy. International Journal of Pharmaceutical Sciences and Nanotechnology, 8(4): 2919-2934. (ISSN : 0974-3278)
  • Sunil Khatak and Harish Dureja, 2015. Recent Techniques and Patents on Solid Lipid Nanoparticles as Novel Carrier for Drug Delivery. Recent Patents on Nanotechnology 2015; 9(3): 150-177. [ISSN (Online): 2212-4020, ISSN (Print) : 1872-2105, Impact Factor : 2.575]
  • Sunil Khatak and Harish Dureja, 2017. Structural Composition of Solid Lipid Nanoparticles for Invasive and Noninvasive Drug Delivery. Current Nanomaterials 2017; 2(3): 129-153. [ISSN (Online): 2405-4623, ISSN (Print): 2405-4615]
  • Sunil Khatak, Mamta Khatak, Frahat Ali, Ashu Rathi, Robin Singh, G.N. Singh and Harish Dureja. Development and Validation of a RP-HPLC Method for Simultaneous Estimation of Antitubercular Drugs in Solid Lipid Nanoparticles. Indian J Pharm Sci 2018; 80(6): 996-1002. (Print: 0250-474X; Online; 1998-3743) Impact Factor: 0.762
  • Sunil Khatak, Uttam Prasad Semwal, Manoj Kumar Pandey and Harish Dureja. Investigation of Antimycobacterial potential of solid lipid nanoparticles against M. smegmatis. The Pharma Innovation Journal 2018; 7(9): 325-329 (Issn 2349-8242 print; 2277-7695 online)


  • BOOKS/BOOK CHAPTER AUTHORED

  • Monika Sachdeva, Rajesh Dholpuria; Remedial Biology ,Nirali Prakashan ,2017 ISBN-13- 9789386943071
  • Monika Sachdeva, Rajesh Dholpuria; Practical book of Remedial Biology ,Nirali Prakashan ,2018 ISBN-13- 9789386943088 Text Book of Medicinal Chemistry (ISBN: 978-93-84588-27-4) Published in 2015 from IK International Publishing house Pvt Ltd, New Delhi. Book is wildly accepted worldwide for pharmacy students and reviewed by Indian Pharmaceutical Association (IPA) in Sept 2018.
  • Vijay Agarwal. Emerging and Patented Analytical Techniques Used for Nanosuspension and Nanocrystal. Importance and Application of Nanotechnology, MedDocs Publishers LLC, Nevada, USA, Volume-II, 2019.
  • Vijay Agarwal, Meenakshi Bajpai, Arundhati Bhattacharya. Solid dosage form of senna leaves powder and their extract, LAP LAMBERT Academic Publishing, Saarbrucken, Germany, 2014 (ISBN: 978-3-8484-0598-5).
  • S. Khatak, H. Dureja. Solid Lipid Nanoparticles in Cancer Chemotherapy. In: H. Dureja. Nanoparticles for the Delivery of Anticancer Agents. LapLambert Academic Publishing, Deutschland, Germany. May, 2016 (ISBN: 9783848405985)

RESEARCH PROMOTION SCHEME PROJECT

The Institute was granted an amount of Rs. 5.0 lac under the Research Promotion Scheme by the Dr. A.P.J. Abdul Kalam Technical University, Lucknow for a research project involving Formulation and Evaluation of Nanosuspension Formulation. The studies are being conducted in the Institute and the findings communicated to the Funding University and Journals



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